Laboratory bioreactor RTS-1

laboratory-scalemultipurposeautomated

RTS-1 overview
RTS-1 is a compact personal bioreactor for aerobic and microaerophilic workflows. It applies patented Reverse-Spin® mechanical mixing in single-use 50 ml tubes and integrates near-infrared (NIR) optical monitoring for non-invasive, real-time tracking of cell growth kinetics.

Features

• Reverse-Spin® mixing in 50 ml Falcon tubes achieves high kLa (up to 450 h-1) suitable for efficient aerobic cultivation
• Individually controlled unit accelerates process optimization and parallel testing
• Supports cultivation of microaerophilic and obligate anaerobic strains (not for strict anaerobic containment)
• Reverse-Spin® enables non-invasive biomass measurement in real time
• Near-infrared optical system (NIR) records growth kinetics without sampling
• Free software for real-time data storage, visualization and analysis
• Compact, low-profile design for benchtop or personal-lab use
• Temperature control and active cooling for rapid setpoint changes and stress experiments
• Task profiling and cycle definition for process automation
• Cloud data storage and remote monitoring via mobile device or PC

Software features

• Real-time cell growth logging
• 3D graphical representation of OD or growth rate over time per unit
• Pause, Save/Load and reporting (PDF, Excel)
• Connect up to 10 units simultaneously to one computer
• Remote monitoring option (internet connection required)
• Cycling/profiling options and user-defined calibration for most cell types

Typical applications

• Fermentation real-time growth kinetics
• Clone candidate screening
• Protein expression monitoring
• Temperature stress and fluctuation experiments
• Media screening and optimization
• Growth characterization
• Inhibition and toxicity testing
• Strain quality control

Technical specifications

• Measurement range: 0–10 OD at 10–20 ml volume (0–19 OD λ600 nm equivalent)
  0–8 OD at 20–30 ml volume (0–15.2 OD λ600 nm equivalent)
• Measurement precision: ±0.3 OD
• Light source: near-infrared (NIR) light diode
• Measurement wavelength (λ): 850 nm
• Measurement periodicity: 1–60 readings per hour
• Culture volume: 10–30 ml
• Temperature setting range: +25°C … +70°C
• Temperature control range: ambient +5°C … +70°C
• Temperature stability: ±0.1°C
• Display: LCD
• Speed control range: 50–2,000 rpm
• Max units per software: 10
• Tube type for aerobic cultivation: 50 ml tube with membrane filter (TubeSpin® Bioreactor 50, TPP®)*
• Tube type for anaerobic cultivation: same as above; other manufacturer tubes of the same type may be used (rotor modification may be required)
• Minimum PC requirements: Intel/AMD processor, 1 GB RAM, Windows 10/11, USB 2.0
• Optimal PC requirements: Intel/AMD processor, 3 GB RAM, Windows 10/11, USB 2.0
• Overall dimensions (W×D×H): 130 × 212 × 200 mm
• Weight: 1.7 kg
• Input current/power consumption: 12 V, 3.3 A / 40 W
• External power supply: Input AC 100–240 V, 50/60 Hz; Output DC 12 V