Simulator for laboratory applications BRS 100i

breathingrespiratory gas

Product overview
BRS 100i is specifically designed for generating neonatal, infant, child and adult breathing patterns required for dose uniformity testing of nebulisers in accordance with ISO 27427:2013. It can also be used to generate the profiles required in USP <1602> for testing Spacers and Valve Holding Chambers (VHCs) used with inhalation aerosols.

Key features

• Ph. Eur. 2.9.44, USP <1601>, <1602> and ISO 27427:2013 compliant
• Intuitive touchscreen user interface
• Extensive data output options
• Capable of generating neonatal, infant, child and adult breathing profiles

Applications / Uses

• Testing nebulisers (Ph. Eur. 2.9.44 and USP <1601>)
• Testing MDIs with spacers/valved holding chambers (USP <1602>)
• Improving in-vitro/in-vivo correlations (IVIVCs) for MDIs with spacers/VHCs and nebulisers: with filter holder and adapter for dose uniformity; with impactor and mixing inlet for APSD

Operation & waveform

• Waveforms: Sinusoidal
• Profile: Inhalation and exhalation
• Start: Select start on inhalation or exhalation stroke

Caractéristiques / Spécifications techniques

• Volume (manually adjust): 0 to 800 mL
• Frequency: 12 – 40 bpm
• I:E ratio: 1:1, 1:2 or 1:3
• Waveforms: Sinusoidal
• Patient profile suitability: Neonate/Infant, Child, Adult
• Profile: Inhalation and Exhalation
• Start: Select start on inhalation or exhalation stroke
• User interface: Touchscreen
• Uses: Testing nebulisers (Ph. Eur. 2.9.44 and USP <1601>); Testing MDIs with Spacers/VHCs (USP <1602>); Improving IVIVCs for MDIs with Spacers/VHCs and nebulisers (Dose Uniformity with Filter Holder and Adapter; APSD with Impactor and Mixing Inlet)