Mass tester Apparatus™ IDA

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Product overview
The Inhaled Dissolution Apparatus™ (IDA) is a dissolution testing system purpose‑built for orally inhaled and nasal products (OIPs). It produces repeatable, comparable dissolution profiles from aerosolised drug samples using a controlled three‑step workflow: Collect – Transfer – Dissolve. The design addresses low collected drug mass and ensures consistent dose capture with OIP‑relevant media volumes and optimised geometry.

Key IDA product highlights

• Repeatable, comparable dissolution data for OIPs
• Discriminatory performance across formulations
• Purpose‑built geometry: reduced‑diameter paddle and flat‑bottom vessel
• Optimised for low media volumes (200–500 mL)
• Flexible inlet compatibility (NGI ports, AINI, FSIs, glass chambers)
• Available in 6‑ and 8‑station configurations
• Automation compatible (integration with Vertus® III)
• Minimised manual sample handling via dedicated filter holder

How the IDA works: a simple 3‑step process

• Step 1: Collect — Aerosolised drug is captured onto a filter using the selected inlet configuration, providing a consistent starting dose for dissolution testing.
• Step 2: Transfer — A bespoke filter holder attaches directly to the dissolution paddle to transfer the collected sample with minimal handling and disturbance.
• Step 3: Dissolve — The filter is lowered into the vessel containing dissolution media and profiling is performed under controlled conditions; the paddle and flat‑bottom vessel support consistent circulation around the filter.

Performance and design rationale
IDAs reduced‑diameter paddle and flat‑bottom vessel preserve circulation around low‑mass samples typical of inhaled product testing. Standardising the Collect > Transfer > Dissolve workflow reduces variability and improves comparability of dissolution profiles across studies and laboratories.

Technical specifications

• Flow rate compatibility: 5–100 L/min
• Flow profile options: constant flow; breathing simulation (tidal / inhalation‑only)
• Inlet compatibility: NGI Induction Port, NGI Preseparator, Fast Screening Impactor, Alberta Idealised Throat, Alberta Idealised Nasal Inlet (AINI), Glass Expansion Chambers
• Stations: 6‑ or 8‑station configurations
• Media volume range: 200–500 mL
• Optimised paddle and flat‑bottom vessel geometry for OIP‑relevant volumes
• Filter holder for direct transfer from collection to paddle (minimised handling)
• Automation compatibility: integration with Vertus® III (automated shake and fire)
• Application: purpose‑built for Orally Inhaled Products (OIPs) dissolution assessment

Applications and suitability
The IDA supports dissolution assessment for a wide range of orally inhaled and nasal drug products. It is compatible with common OIP collection interfaces and can operate in constant flow setups or with breathing simulation profiles to align collection conditions with test objectives.